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Combination therapy of cancer with cancer vaccine and immune checkpoint inhibitors: A mathematical model

In this paper we consider a combination therapy of cancer. One drug is a vaccine which activates dendritic cells so that they induce more T cells to infiltrate the tumor. The other drug is a checkpoint inhibitor, which enables the T cells to remain active against the cancer cells. The two drugs are...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Lai, Xiulan, Friedman, Avner
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444846/
https://ncbi.nlm.nih.gov/pubmed/28542574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178479
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