Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques

Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV subcutaneously to four pregnant rhesus macaques. While non-pregnant animals in a previous study contemporary with the current report...

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Vydáno v:PLoS Pathog
Hlavní autoři: Nguyen, Sydney M., Antony, Kathleen M., Dudley, Dawn M., Kohn, Sarah, Simmons, Heather A., Wolfe, Bryce, Salamat, M. Shahriar, Teixeira, Leandro B. C., Wiepz, Gregory J., Thoong, Troy H., Aliota, Matthew T., Weiler, Andrea M., Barry, Gabrielle L., Weisgrau, Kim L., Vosler, Logan J., Mohns, Mariel S., Breitbach, Meghan E., Stewart, Laurel M., Rasheed, Mustafa N., Newman, Christina M., Graham, Michael E., Wieben, Oliver E., Turski, Patrick A., Johnson, Kevin M., Post, Jennifer, Hayes, Jennifer M., Schultz-Darken, Nancy, Schotzko, Michele L., Eudailey, Josh A., Permar, Sallie R., Rakasz, Eva G., Mohr, Emma L., Capuano, Saverio, Tarantal, Alice F., Osorio, Jorge E., O’Connor, Shelby L., Friedrich, Thomas C., O’Connor, David H., Golos, Thaddeus G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444831/
https://ncbi.nlm.nih.gov/pubmed/28542585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006378
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