Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques

Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV subcutaneously to four pregnant rhesus macaques. While non-pregnant animals in a previous study contemporary with the current report...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Nguyen, Sydney M., Antony, Kathleen M., Dudley, Dawn M., Kohn, Sarah, Simmons, Heather A., Wolfe, Bryce, Salamat, M. Shahriar, Teixeira, Leandro B. C., Wiepz, Gregory J., Thoong, Troy H., Aliota, Matthew T., Weiler, Andrea M., Barry, Gabrielle L., Weisgrau, Kim L., Vosler, Logan J., Mohns, Mariel S., Breitbach, Meghan E., Stewart, Laurel M., Rasheed, Mustafa N., Newman, Christina M., Graham, Michael E., Wieben, Oliver E., Turski, Patrick A., Johnson, Kevin M., Post, Jennifer, Hayes, Jennifer M., Schultz-Darken, Nancy, Schotzko, Michele L., Eudailey, Josh A., Permar, Sallie R., Rakasz, Eva G., Mohr, Emma L., Capuano, Saverio, Tarantal, Alice F., Osorio, Jorge E., O’Connor, Shelby L., Friedrich, Thomas C., O’Connor, David H., Golos, Thaddeus G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444831/
https://ncbi.nlm.nih.gov/pubmed/28542585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006378
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