Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats

Successful drug therapies for treating ocular diseases require effective concentrations of neuroprotective compounds maintained over time at the site of action. The purpose of this work was to assess the efficacy of intravitreal controlled delivery of tauroursodeoxycholic acid (TUDCA) encapsulated i...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Fernández-Sánchez, Laura, Bravo-Osuna, Irene, Lax, Pedro, Arranz-Romera, Alicia, Maneu, Victoria, Esteban-Pérez, Sergio, Pinilla, Isabel, Puebla-González, María del Mar, Herrero-Vanrell, Rocío, Cuenca, Nicolás
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444790/
https://ncbi.nlm.nih.gov/pubmed/28542454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177998
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