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Thermodynamic framework to assess low abundance DNA mutation detection by hybridization

The knowledge of genomic DNA variations in patient samples has a high and increasing value for human diagnostics in its broadest sense. Although many methods and sensors to detect or quantify these variations are available or under development, the number of underlying physico-chemical detection pri...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Willems, Hanny, Jacobs, An, Hadiwikarta, Wahyu Wijaya, Venken, Tom, Valkenborg, Dirk, Van Roy, Nadine, Vandesompele, Jo, Hooyberghs, Jef
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444680/
https://ncbi.nlm.nih.gov/pubmed/28542229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177384
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