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Regulating dynamic signaling between hematopoietic stem cells and niche cells via a hydrogel matrix

Hematopoietic stem cells (HSC) reside in unique bone marrow niches and are influenced by signals from surrounding cells, the extracellular matrix (ECM), ECM-bound or diffusible biomolecules. Here we describe the use of a three-dimensional hydrogel to alter the balance of HSC-generated autocrine feed...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Mahadik, Bhushan P., Bharadwaj, Narayanan A.K., Ewoldt, Randy H., Harley, Brendan A.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444543/
https://ncbi.nlm.nih.gov/pubmed/28231508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.02.013
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