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Spontaneous chitin accumulation in airways and age-related fibrotic lung disease

The environmentally widespread polysaccharide chitin is degraded and recycled by ubiquitous bacterial and fungal chitinases. Although vertebrates express active chitinases from evolutionarily conserved loci, their role in mammalian physiology is unclear. We show that distinct lung epithelial cells s...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Van Dyken, Steven J., Liang, Hong-Erh, Naikawadi, Ram P., Woodruff, Prescott G., Wolters, Paul J., Erle, David J., Locksley, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444468/
https://ncbi.nlm.nih.gov/pubmed/28431248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.03.044
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