Spontaneous chitin accumulation in airways and age-related fibrotic lung disease

The environmentally widespread polysaccharide chitin is degraded and recycled by ubiquitous bacterial and fungal chitinases. Although vertebrates express active chitinases from evolutionarily conserved loci, their role in mammalian physiology is unclear. We show that distinct lung epithelial cells s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Van Dyken, Steven J., Liang, Hong-Erh, Naikawadi, Ram P., Woodruff, Prescott G., Wolters, Paul J., Erle, David J., Locksley, Richard M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444468/
https://ncbi.nlm.nih.gov/pubmed/28431248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.03.044
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