Sodium Channel Na(v)1.8 Underlies TTX-Resistant Axonal Action Potential Conduction in Somatosensory C-Fibers of Distal Cutaneous Nerves

Voltage-gated sodium (Na(V)) channels are responsible for the initiation and conduction of action potentials within primary afferents. The nine Na(V) channel isoforms recognized in mammals are often functionally divided into tetrodotoxin (TTX)-sensitive (TTX-s) channels (Na(V)1.1–Na(V)1.4, Na(V)1.6–...

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Vydáno v:J Neurosci
Hlavní autoři: Klein, Amanda H., Vyshnevska, Alina, Hartke, Timothy V., De Col, Roberto, Mankowski, Joseph L., Turnquist, Brian, Bosmans, Frank, Reeh, Peter W., Schmelz, Martin, Carr, Richard W., Ringkamp, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2017
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444201/
https://ncbi.nlm.nih.gov/pubmed/28450535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3799-16.2017
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