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Mediation of Movement-Induced Breakthrough Cancer Pain by IB4-Binding Nociceptors in Rats

Cancer-induced bone pain is characterized by moderate to severe ongoing pain that commonly requires the use of opiates. Even when ongoing pain is well controlled, patients can suffer breakthrough pain (BTP), episodic severe pain that “breaks through” the medication. We developed a novel model of can...

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Pubblicato in:J Neurosci
Autori principali: Havelin, Joshua, Imbert, Ian, Sukhtankar, Devki, Remeniuk, Bethany, Pelletier, Ian, Gentry, Jonathan, Okun, Alec, Tiutan, Timothy, Porreca, Frank, King, Tamara E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444195/
https://ncbi.nlm.nih.gov/pubmed/28438966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1212-16.2017
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