New approaches to eliciting protective immunity through T cell repertoire manipulation: the concept of thymic vaccination

Conventional vaccines afford protection against infectious diseases by expanding existing pathogen-specific peripheral lymphocytes, both CD8 cytotoxic effector (CTL) and CD4 helper T cells. The latter induce B cell maturation and antibody production. As a consequence, lymphocytes within the memory p...

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Pubblicato in:	Med Immunol
Autori principali:	Fridkis-Hareli, Masha, Reinherz, Ellis L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2004
Soggetti:	Commentary
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15588284/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1476-9433-3-2
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