Long-Term, Stochastic Editing of Regenerative Anatomy via Targeting Endogenous Bioelectric Gradients

We show that regenerating planarians’ normal anterior-posterior pattern can be permanently rewritten by a brief perturbation of endogenous bioelectrical networks. Temporary modulation of regenerative bioelectric dynamics in amputated trunk fragments of planaria stochastically results in a constant r...

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Foilsithe in:Biophys J
Main Authors: Durant, Fallon, Morokuma, Junji, Fields, Christopher, Williams, Katherine, Adams, Dany Spencer, Levin, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2017
Ábhair:
Systems Biophysics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443973/
https://ncbi.nlm.nih.gov/pubmed/28538159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.04.011
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