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Using bicistronic constructs to evaluate the chaperone activities of heat shock proteins in cells

Heat shock proteins (Hsps) are molecular chaperones that prevent the aggregation of client proteins by facilitating their refolding, or trafficking them for degradation. The chaperone activities of Hsps are dependent on dynamic protein-protein interactions, including their oligomerisation into large...

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Bibliographic Details
Published in:Sci Rep
Main Authors: San Gil, Rebecca, Berg, Tracey, Ecroyd, Heath
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443837/
https://ncbi.nlm.nih.gov/pubmed/28539657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02459-9
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