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The human asparaginase enzyme (ASPG) inhibits growth in leukemic cells

The human protein ASPG is an enzyme with a putative antitumor activity. We generated in bacteria and then purified a recombinant GST-ASPG protein that we used to characterize the biochemical and cytotoxic properties of the human ASPG. We demonstrated that ASPG possesses asparaginase and PAF acetylhy...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Belviso, Stefania, Iuliano, Rodolfo, Amato, Rosario, Perrotti, Nicola, Menniti, Miranda
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443537/
https://ncbi.nlm.nih.gov/pubmed/28542249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178174
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