Development of peptidomimetic inhibitors of the ERG gene fusion product in prostate cancer

Transcription factors play a key role in the development of diverse cancers, and therapeutically targeting them has remained a challenge. In prostate cancer, the gene encoding the transcription factor ERG is recurrently rearranged and plays a critical role in prostate oncogenesis. Here, we identifie...

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Publicado no:Cancer Cell
Main Authors: Wang, Xiaoju, Qiao, Yuanyuan, Asangani, Irfan A., Ateeq, Bushra, Poliakov, Anton, Cieślik, Marcin, Pitchiaya, Sethuramasundaram, Chakravarthi, Balabhadrapatruni V. S. K., Cao, Xuhong, Jing, Xiaojun, Wang, Cynthia X., Apel, Ingrid J., Wang, Rui, Tien, Jean Ching-Yi, Juckette, Kristin M., Yan, Wei, Jiang, Hui, Wang, Shaomeng, Varambally, Sooryanarayana, Chinnaiyan, Arul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443258/
https://ncbi.nlm.nih.gov/pubmed/28344039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.02.017
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