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Effects of caffeine on cell viability and activity of histone deacetylase 1 and histone acetyltransferase in glioma cells

OBJECTIVE: The prognosis of patients with glioblastoma remains poor even after various treatments such as surgery, radiotherapy, and chemotherapy. Thus, development of new drugs is urgently needed. The mechanisms underlying the cytotoxicity of caffeine in glioma cells are not clearly understood. Thi...

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Bibliographische Detailangaben
Veröffentlicht in:Tzu Chi Med J
Hauptverfasser: Chen, Jin-Cherng, Hwang, Juen-Haur
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442913/
https://ncbi.nlm.nih.gov/pubmed/28757735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcmj.2016.06.005
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