Mechanisms of p53 loss in human sarcomas.
An important role for the p53 gene in neoplastic transformation in vitro and in vivo has been imputed by functional studies and identification of tumor-acquired gene defects or alterations in its expression. To study the generality and mechanisms of p53 alteration in human cancer, we examined 241 tu...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1990
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2143022/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.15.5863 |
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