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Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins

Recruitment and activation of polymorphonuclear neutrophils (PMNs) reflects a primary immunological response to invading pathogens and has also emerged as a hallmark of vascular inflammation. One of the principal enzymes released upon PMN activation is myeloperoxidase (MPO), a heme protein that not...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lau, Denise, Mollnau, Hanke, Eiserich, Jason P., Freeman, Bruce A., Daiber, Andreas, Gehling, Ursula M., Brümmer, Jens, Rudolph, Volker, Münzel, Thomas, Heitzer, Thomas, Meinertz, Thomas, Baldus, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544285/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15625114/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0405193102
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