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CD98hc (SLC3A2) mediates integrin signaling

Integrins regulate cellular behaviors through signaling pathways, including Rho GTPases and kinases. CD98 heterodimers, comprised of a heavy chain (CD98hc, SLC3A2) and one of several light chains, interact with integrins through CD98hc. CD98hc overexpression leads to anchorage-independent cell growt...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Feral, Chloe C., Nishiya, Naoyuki, Fenczik, Csilla A., Stuhlmann, Heidi, Slepak, Marina, Ginsberg, Mark H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544283/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15625115/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404852102
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