Notch‐Expanded Murine Hematopoietic Stem and Progenitor Cells Mitigate Death from Lethal Radiation and Convey Immune Tolerance in Mismatched Recipients

The hematopoietic syndrome of acute radiation syndrome (h‐ARS) is characterized by severe bone marrow aplasia, resulting in a significant risk for bleeding, infections, and death. To date, clinical management of h‐ARS is limited to supportive care dictated by the level of radiation exposure, with a...

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Detalles Bibliográficos
Publicado en:Stem Cells Transl Med
Main Authors: Milano, Filippo, Merriam, Fabiola, Nicoud, Ian, Li, Jianqiang, Gooley, Ted A., Heimfeld, Shelly, Imren, Suzan, Delaney, Colleen
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Translational Research Articles and Reviews
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442821/
https://ncbi.nlm.nih.gov/pubmed/28191773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2016-0112
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