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Metabolic Genetic Screens Reveal Multidimensional Regulation of Virulence Gene Expression in Listeria monocytogenes and an Aminopeptidase That Is Critical for PrfA Protein Activation

Listeria monocytogenes is an environmental saprophyte and intracellular bacterial pathogen. Upon invading mammalian cells, the bacterium senses abrupt changes in its metabolic environment, which are rapidly transduced to regulation of virulence gene expression. To explore the relationship between L....

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Friedman, Sivan, Linsky, Marika, Lobel, Lior, Rabinovich, Lev, Sigal, Nadejda, Herskovits, Anat A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442619/
https://ncbi.nlm.nih.gov/pubmed/28396325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00027-17
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