Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca(2+) Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK

Several new therapeutic options emerged recently to treat metastatic melanoma; however, the high frequency of intrinsic and acquired resistance among patients shows a need for new therapeutic options. Previously, we identified the plasma membrane Ca(2+) ATPase 4b (PMCA4b) as a metastasis suppressor...

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Udgivet i:Front Oncol
Main Authors: Hegedüs, Luca, Padányi, Rita, Molnár, Judit, Pászty, Katalin, Varga, Karolina, Kenessey, István, Sárközy, Eszter, Wolf, Matthias, Grusch, Michael, Hegyi, Zoltán, Homolya, László, Aigner, Clemens, Garay, Tamás, Hegedüs, Balázs, Tímár, József, Kállay, Enikö, Enyedi, Ágnes
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442207/
https://ncbi.nlm.nih.gov/pubmed/28596940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2017.00095
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