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A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens

A key aspect to finding an efficacious human immunodeficiency virus (HIV) vaccine is the optimization of vaccine schedules that can mediate the efficient maturation of protective immune responses. In the present study, we investigated the effect of alternate booster regimens on the immune responses...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Kratochvil, Sven, McKay, Paul F., Kopycinski, Jakub T., Bishop, Cynthia, Hayes, Peter John, Muir, Luke, Pinder, Christopher L., Cizmeci, Deniz, King, Deborah, Aldon, Yoann, Wines, Bruce D., Hogarth, P. Mark, Chung, Amy W., Kent, Stephen J., Held, Kathrin, Geldmacher, Christof, Dally, Len, Santos, Nelson S., Cole, Tom, Gilmour, Jill, Fidler, Sarah, Shattock, Robin J.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442169/
https://ncbi.nlm.nih.gov/pubmed/28596770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00595
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