Genetic variants in the transcription regulatory region of MEGF10 are associated with autism in Chinese Han population

Multiple epidermal growth factor-like-domains 10 (MEGF10), a critical member of the apoptotic engulfment pathway, mediates axon pruning and synapse elimination during brain development. Previous studies indicated that synaptic pruning deficit was associated with autism-related phenotypes. However, t...

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Udgivet i:Sci Rep
Main Authors: Wu, Zhiliu, Qin, Jian, You, Yang, Ma, Yuanlin, Jia, Meixiang, Wang, Linyan, Lu, Tianlan, Yue, Weihua, Ruan, Yanyan, Zhang, Dai, Li, Jun, Wang, Lifang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442155/
https://ncbi.nlm.nih.gov/pubmed/28536440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02348-1
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