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Symmetry‐breaking in branching epithelia: cells on micro‐patterns under flow challenge the hypothesis of positive feedback by a secreted autocrine inhibitor of motility
Branching morphogenesis of epithelia involves division of cells into leader (tip) and follower (stalk) cells. Published work on cell lines in culture has suggested that symmetry‐breaking takes place via a secreted autocrine inhibitor of motility, the inhibitor accumulating more in concave regions of...
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| Veröffentlicht in: | J Anat |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5442143/ https://ncbi.nlm.nih.gov/pubmed/28369863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12599 |
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