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Surface PEGylation of Mesoporous Silica Nanorods (MSNR): Effect on loading, release, and delivery of mitoxantrone in hypoxic cancer cells

Mesoporous silica nanomaterials show great potential to deliver chemotherapeutics for cancer treatment. The key challenges in the development of injectable mesoporous silica formulations are colloidal instability, hemolysis and inefficient drug loading and release. In this study, we evaluated the ef...

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Pubblicato in:Sci Rep
Autori principali: Wani, Amit, Savithra, Galbokka H. Layan, Abyad, Ayat, Kanvinde, Shrey, Li, Jing, Brock, Stephanie, Oupický, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442097/
https://ncbi.nlm.nih.gov/pubmed/28536462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02531-4
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