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Surface PEGylation of Mesoporous Silica Nanorods (MSNR): Effect on loading, release, and delivery of mitoxantrone in hypoxic cancer cells

Mesoporous silica nanomaterials show great potential to deliver chemotherapeutics for cancer treatment. The key challenges in the development of injectable mesoporous silica formulations are colloidal instability, hemolysis and inefficient drug loading and release. In this study, we evaluated the ef...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wani, Amit, Savithra, Galbokka H. Layan, Abyad, Ayat, Kanvinde, Shrey, Li, Jing, Brock, Stephanie, Oupický, David
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442097/
https://ncbi.nlm.nih.gov/pubmed/28536462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02531-4
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