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Unfair competition governs the interaction of pCPI-17 with myosin phosphatase (PP1-MYPT1)

The small phosphoprotein pCPI-17 inhibits myosin light-chain phosphatase (MLCP). Current models postulate that during muscle relaxation, phosphatases other than MLCP dephosphorylate and inactivate pCPI-17 to restore MLCP activity. We show here that such hypotheses are insufficient to account for the...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Filter, Joshua J, Williams, Byron C, Eto, Masumi, Shalloway, David, Goldberg, Michael L
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441869/
https://ncbi.nlm.nih.gov/pubmed/28387646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24665
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