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Efficiency of Database Search for Identification of Mutated and Modified Proteins via Mass Spectrometry

Although protein identification by matching tandem mass spectra (MS/MS) against protein databases is a widespread tool in mass spectrometry, the question about reliability of such searches remains open. Absence of rigorous significance scores in MS/MS database search makes it difficult to discard ra...

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Detalhes bibliográficos
Main Authors: Pevzner, Pavel A., Mulyukov, Zufar, Dancik, Vlado, Tang, Chris L
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544186/
https://ncbi.nlm.nih.gov/pubmed/11157792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.154101
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