Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1–targeted therapy in lung cancer patients

Exhausted T cells in chronic infections and cancer have sustained expression of the inhibitory receptor programmed cell death 1 (PD-1). Therapies that block the PD-1 pathway have shown promising clinical results in a significant number of advanced-stage cancer patients. Nonetheless, a better underst...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Kamphorst, Alice O., Pillai, Rathi N., Yang, Shu, Nasti, Tahseen H., Akondy, Rama S., Wieland, Andreas, Sica, Gabriel L., Yu, Ke, Koenig, Lydia, Patel, Nikita T., Behera, Madhusmita, Wu, Hong, McCausland, Megan, Chen, Zhengjia, Zhang, Chao, Khuri, Fadlo R., Owonikoko, Taofeek K., Ahmed, Rafi, Ramalingam, Suresh S.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441721/
https://ncbi.nlm.nih.gov/pubmed/28446615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705327114
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki