Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis.

Suspensions rich in pancreatic beta cells were transfected by means of electroporation or by using the liposome technique with DNA constructs coding for the B chain of platelet-derived growth factor (PDGF) and the PDGF alpha and beta receptors to induce a mitotic response in this slowly replicating...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Welsh, M, Claesson-Welsh, L, Hallberg, A, Welsh, N, Betsholtz, C, Arkhammar, P, Nilsson, T, Heldin, C H, Berggren, P O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2165603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.15.5807
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