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Molecular Analysis Reveals Localization of Saccharomyces cerevisiae Protein Kinase C to Sites of Polarized Growth and Pkc1p Targeting to the Nucleus and Mitotic Spindle

The catalytic activity and intracellular localization of protein kinase C (PKC) are both highly regulated in vivo. This family of kinases contains conserved regulatory motifs, i.e., the C1, C2, and HR1 domains, which target PKC isoforms to specific subcellular compartments and restrict their activit...

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Detalhes bibliográficos
Main Authors: Denis, Valérie, Cyert, Martha S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544167/
https://ncbi.nlm.nih.gov/pubmed/15643058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.4.1.36-45.2005
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