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Concordance of bioactive vs. total immunoreactive serum leptin levels in children with severe early onset obesity
CONTEXT: Leptin secreted from adipose tissue signals peripheral energy status to the brain. Monogenic leptin deficiency results in severe early onset obesity with hyperphagia. Recently, a similar phenotype of inactivating leptin mutations but with preserved immunoreactivity and hence normal circulat...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5441582/ https://ncbi.nlm.nih.gov/pubmed/28542631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178107 |
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