Generating testable hypotheses for schizophrenia and rheumatoid arthritis pathogenesis by integrating epidemiological, genomic, and protein interaction data

Patients with schizophrenia and their relatives have reduced prevalence of rheumatoid arthritis. Schizophrenia and rheumatoid arthritis genome-wide association studies also indicate negative genetic correlations, suggesting that there may be shared pathogenesis at the DNA level or downstream. A port...

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Pubblicato in:NPJ Schizophr
Autori principali: Malavia, Tulsi A., Chaparala, Srilakshmi, Wood, Joel, Chowdari, Kodavali, Prasad, Konasale M., McClain, Lora, Jegga, Anil G., Ganapathiraju, Madhavi K., Nimgaonkar, Vishwajit L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441529/
https://ncbi.nlm.nih.gov/pubmed/28560257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41537-017-0010-z
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