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In vitro clearance of doxorubicin with a DNA-based filtration device designed for intravascular use with intra-arterial chemotherapy

To report a novel method using immobilized DNA within mesh to sequester drugs that have intrinsic DNA binding characteristics directly from flowing blood. DNA binding experiments were carried out in vitro with doxorubicin in saline (PBS solution), porcine serum, and porcine blood. Genomic DNA was us...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Biomed Microdevices
المؤلفون الرئيسيون:	Aboian, Mariam S., Yu, Jay F., Gautam, Ayushi, Sze, Chia-Hung, Yang, Jeffrey K., Chan, Jonathan, Lillaney, Prasheel V., Jordan, Caroline D., Oh, Hee-Jeung, Wilson, David M., Patel, Anand S., Wilson, Mark W., Hetts, Steven W.
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	2016
الموضوعات:	Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5441460/ https://ncbi.nlm.nih.gov/pubmed/27778226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10544-016-0124-5
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In vitro clearance of doxorubicin with a DNA-based filtration device designed for intravascular use with intra-arterial chemotherapy

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