In vitro clearance of doxorubicin with a DNA-based filtration device designed for intravascular use with intra-arterial chemotherapy

To report a novel method using immobilized DNA within mesh to sequester drugs that have intrinsic DNA binding characteristics directly from flowing blood. DNA binding experiments were carried out in vitro with doxorubicin in saline (PBS solution), porcine serum, and porcine blood. Genomic DNA was us...

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Publicado en:Biomed Microdevices
Autores principales: Aboian, Mariam S., Yu, Jay F., Gautam, Ayushi, Sze, Chia-Hung, Yang, Jeffrey K., Chan, Jonathan, Lillaney, Prasheel V., Jordan, Caroline D., Oh, Hee-Jeung, Wilson, David M., Patel, Anand S., Wilson, Mark W., Hetts, Steven W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441460/
https://ncbi.nlm.nih.gov/pubmed/27778226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10544-016-0124-5
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