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Structural and mechanistic insights into homocysteine degradation by a mutant of methionine γ‐lyase based on substrate‐assisted catalysis
Methionine γ‐lyse (MGL) catalyzes the α, γ‐elimination of l‐methionine and its derivatives as well as the α, β‐elimination of l‐cysteine and its derivatives to produce α‐keto acids, volatile thiols, and ammonia. The reaction mechanism of MGL has been characterized by enzymological studies using seve...
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| Publicat a: | Protein Sci |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5441414/ https://ncbi.nlm.nih.gov/pubmed/28329912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3158 |
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