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Stabilization of 4E-BP1 by PI3K kinase and its involvement in CHK2 phosphorylation in the cellular response to radiation

Objectives: 4E-BP1 is a family member of eIF4E binding proteins (4E-BPs) which act as the suppressors of cap-dependent translation of RNA via competitively associating with cap-bound eIF4E. RNA translation regulation is an important manner to control the cellular responses to a series of stress cond...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Yu, Zi-Jian, Luo, Hui-Hui, Shang, Zeng-Fu, Guan, Hua, Xiao, Bei-Bei, Liu, Xiao-Dan, Wang, Yu, Huang, Bo, Zhou, Ping-Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441037/
https://ncbi.nlm.nih.gov/pubmed/28539821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.18329
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