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Role of the Simian Virus 5 Fusion Protein N-Terminal Coiled-Coil Domain in Folding and Promotion of Membrane Fusion

Formation of a six-helix bundle comprised of three C-terminal heptad repeat regions in antiparallel orientation in the grooves of an N-terminal coiled-coil is critical for promotion of membrane fusion by paramyxovirus fusion (F) proteins. We have examined the effect of mutations in four residues of...

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Detalles Bibliográficos
Main Authors: West, Dava S., Sheehan, Michael S., Segeleon, Patrick K., Dutch, Rebecca Ellis
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC544100/
https://ncbi.nlm.nih.gov/pubmed/15650180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1543-1551.2005
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