Perfusion by Arterial Spin labelling following Single dose Tadalafil In Small vessel disease (PASTIS): study protocol for a randomised controlled trial

BACKGROUND: Cerebral small vessel disease is a common cause of vascular cognitive impairment in older people, with no licensed treatment. Cerebral blood flow is reduced in small vessel disease. Tadalafil is a widely prescribed phosphodiesterase-5 inhibitor that increases blood flow in other vascular...

詳細記述

保存先:
書誌詳細
出版年:Trials
主要な著者: Pauls, Mathilde M. H., Clarke, Natasha, Trippier, Sarah, Betteridge, Shai, Howe, Franklyn A., Khan, Usman, Kruuse, Christina, Madigan, Jeremy B., Moynihan, Barry, Pereira, Anthony C., Rolfe, Debbie, Rostrup, Egill, Haig, Caroline E., Barrick, Thomas R., Isaacs, Jeremy D., Hainsworth, Atticus H.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2017
主題:
Study Protocol
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440904/
https://ncbi.nlm.nih.gov/pubmed/28532471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-1973-9
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