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The Phosphorylation Status of the Serine-Rich Region of the Human Cytomegalovirus 86-Kilodalton Major Immediate-Early Protein IE2/IEP86 Affects Temporal Viral Gene Expression

The 86-kDa major immediate-early protein (IE2/IEP86) of human cytomegalovirus (HCMV) contains a serine-rich region (amino acids 258 to 275) with several consensus casein kinase II (CKII) sites. We performed extensive mutational analysis of this region, changing serines to alternating alanines and gl...

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Detalhes bibliográficos
Main Authors: Barrasa, M. Inmaculada, Harel, Noam Y., Alwine, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544087/
https://ncbi.nlm.nih.gov/pubmed/15650169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1428-1437.2005
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