Association Between N363S and BclI Polymorphisms of the Glucocorticoid Receptor Gene (NR3C1) and Glucocorticoid Side Effects During Childhood Acute Lymphoblastic Leukemia Treatment

OBJECTIVE: Glucocorticoids (GCs) are the key drugs for the treatment of pediatric acute lymphoblastic leukemia (ALL). Herein, investigation of the relationship between the N363S and BclI polymorphisms of the GC receptor gene (NR3C1) and the side effects of GCs during pediatric ALL therapy was aimed....

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Veröffentlicht in:Turk J Haematol
Hauptverfasser: Kaymak Cihan, Meriç, Karabulut, Halil Gürhan, Yürür Kutlay, Nüket, Ilgın Ruhi, Hatice, Tükün, Ajlan, Olcay, Lale
Format: Artigo
Sprache:Inglês
Veröffentlicht: Galenos Publishing 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440867/
https://ncbi.nlm.nih.gov/pubmed/28179212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.2016.0253
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