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Acute Knockdown of Kv4.1 Regulates Repetitive Firing Rates and Clock Gene Expression in the Suprachiasmatic Nucleus and Daily Rhythms in Locomotor Behavior

Rapidly activating and inactivating A-type K(+) currents (I(A)) encoded by Kv4.2 and Kv4.3 pore-forming (α) subunits of the Kv4 subfamily are key regulators of neuronal excitability. Previous studies have suggested a role for Kv4.1 α-subunits in regulating the firing properties of mouse suprachiasma...

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Publicat a:eNeuro
Autors principals: Hermanstyne, Tracey O., Granados-Fuentes, Daniel, Mellor, Rebecca L., Herzog, Erik D., Nerbonne, Jeanne M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440767/
https://ncbi.nlm.nih.gov/pubmed/28560311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0377-16.2017
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