Endometrial cancer is a receptor-mediated target for Mullerian Inhibiting Substance

Mullerian Inhibiting Substance (MIS), a 140-kDa homodimer glycoprotein member of the TGF-β superfamily of biological-response modifiers, causes regression of the Mullerian ducts in developing male embryos. MIS also can induce growth arrest and apoptosis in ovarian and cervical cancer cell lines. The...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Renaud, Elizabeth J., MacLaughlin, David T., Oliva, Esther, Rueda, Bo R., Donahoe, Patricia K.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15618407/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0407772101
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