YAP regulates cell mechanics by controlling focal adhesion assembly

Hippo effectors YAP/TAZ act as on–off mechanosensing switches by sensing modifications in extracellular matrix (ECM) composition and mechanics. The regulation of their activity has been described by a hierarchical model in which elements of Hippo pathway are under the control of focal adhesions (FAs...

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Publicat a:Nat Commun
Autors principals: Nardone, Giorgia, Oliver-De La Cruz, Jorge, Vrbsky, Jan, Martini, Cecilia, Pribyl, Jan, Skládal, Petr, Pešl, Martin, Caluori, Guido, Pagliari, Stefania, Martino, Fabiana, Maceckova, Zuzana, Hajduch, Marian, Sanz-Garcia, Andres, Pugno, Nicola Maria, Stokin, Gorazd Bernard, Forte, Giancarlo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440673/
https://ncbi.nlm.nih.gov/pubmed/28504269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15321
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