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Propagation of an infertile hermaphrodite mouse lacking germ cells by using nuclear transfer and embryonic stem cell technology

Animals generated by systematic mutagenesis and routine breeding are often infertile because they lack germ cells, and maintenance of such lines of animals has been impossible. We found a hermaphrodite infertile mouse in our colony, a genetic male with an abnormal Y chromosome lacking developing ger...

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Autori principali: Wakayama, Sayaka, Kishigami, Satoshi, Van Thuan, Nguyen, Ohta, Hiroshi, Hikichi, Takafusa, Mizutani, Eiji, Yanagimachi, Ryuzo, Wakayama, Teruhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC544064/
https://ncbi.nlm.nih.gov/pubmed/15618395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408548102
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