Propagation of an infertile hermaphrodite mouse lacking germ cells by using nuclear transfer and embryonic stem cell technology

Animals generated by systematic mutagenesis and routine breeding are often infertile because they lack germ cells, and maintenance of such lines of animals has been impossible. We found a hermaphrodite infertile mouse in our colony, a genetic male with an abnormal Y chromosome lacking developing ger...

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Detalhes bibliográficos
Main Authors: Wakayama, Sayaka, Kishigami, Satoshi, Van Thuan, Nguyen, Ohta, Hiroshi, Hikichi, Takafusa, Mizutani, Eiji, Yanagimachi, Ryuzo, Wakayama, Teruhiko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544064/
https://ncbi.nlm.nih.gov/pubmed/15618395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408548102
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