MyD88-dependent induction of allergic Th2 responses to intranasal antigen

MyD88 is a common Toll-like receptor (TLR) adaptor molecule found to be essential for induction of adaptive Th1 immunity. Conversely, innate control of adaptive Th2 immunity has been shown to occur in a MyD88-independent manner. In this study, we show that MyD88 is an essential innate component in t...

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Detalhes bibliográficos
Main Authors: Piggott, Damani A., Eisenbarth, Stephanie C., Xu, Lan, Constant, Stephanie L., Huleatt, James W., Herrick, Christina A., Bottomly, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544038/
https://ncbi.nlm.nih.gov/pubmed/15650773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522462
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