Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis

B cell chronic lymphocytic leukemia (B-CLL) is a neoplastic disorder characterized by accumulation of B lymphocytes due to uncontrolled growth and resistance to apoptosis. Analysis of B cells freshly isolated from 40 patients with chronic lymphocytic leukemia demonstrated that the Src kinase Lyn, th...

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Hauptverfasser: Contri, Antonella, Brunati, Anna Maria, Trentin, Livio, Cabrelle, Anna, Miorin, Marta, Cesaro, Luca, Pinna, Lorenzo A., Zambello, Renato, Semenzato, Gianpietro, Donella-Deana, Arianna
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC544036/
https://ncbi.nlm.nih.gov/pubmed/15650771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522094
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