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Rejoining of DNA Double-Strand Breaks as a Function of Overhang Length

The ends of spontaneously occurring double-strand breaks (DSBs) may contain various lengths of single-stranded DNA, blocking lesions, and gaps and flaps generated by end annealing. To investigate the processing of such structures, we developed an assay in which annealed oligonucleotides are ligated...

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Main Authors: Daley, James M., Wilson, Thomas E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC544009/
https://ncbi.nlm.nih.gov/pubmed/15657419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.3.896-906.2005
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