Evaluation of somatostatin and nucleolin receptors for therapeutic delivery in non-small cell lung cancer stem cells applying the somatostatin-analog DOTATATE and the nucleolin-targeting aptamer AS1411

Cancer stem cells represent the putative tumor-driving subpopulation thought to account for drug resistance, relapse, and metastatic spread of epithelial and other cancer types. Accordingly, cell surface markers for therapeutic delivery to cancer stem cells are subject of intense research. Somatosta...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Holmboe, Sif, Hansen, Pernille Lund, Thisgaard, Helge, Block, Ines, Müller, Carolin, Langkjær, Niels, Høilund-Carlsen, Poul Flemming, Olsen, Birgitte Brinkmann, Mollenhauer, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440050/
https://ncbi.nlm.nih.gov/pubmed/28542563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178286
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