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Cisplatin induces protective autophagy through activation of BECN1 in human bladder cancer cells

PURPOSE: Cisplatin-based chemotherapy is the first line treatment for several cancers including bladder cancer (BC). Autophagy induction has been implied to contribute to cisplatin resistance in ovarian cancer; and a high basal level of autophagy has been demonstrated in human bladder tumors. Theref...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Lin, Ji-Fan, Lin, Yi-Chia, Tsai, Te-Fu, Chen, Hung-En, Chou, Kuang-Yu, Hwang, Thomas I-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439993/
https://ncbi.nlm.nih.gov/pubmed/28553083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S126464
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