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Benzo[a]pyrene activates interleukin-6 induction and suppresses nitric oxide-induced apoptosis in rat vascular smooth muscle cells

Benzo[a]pyrene, a ubiquitous environmental pollutant, has been suggested to be capable of initiating and/or accelerating atherosclerosis. Accumulation of vascular smooth muscle cells (VSMCs) in vessel intima is a hallmark of atherosclerosis. Nitric oxide (NO) can suppress VSMCs proliferation and ind...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tzeng, Huei-Ping, Lan, Kuo-Cheng, Yang, Ting-Hua, Chung, Min-Ni, Liu, Shing Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439712/
https://ncbi.nlm.nih.gov/pubmed/28531207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178063
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